Standard sequences

Structural #

T1-weighted #

MPRAGE #

High resolution, T₁-weighted, structural MRI

Parameter	Value
Acquisition time	4 min 32 s
Type	3D (sagittal slices)
FOV (A-P x L-R x F-H)	256 mm x 192 mm x 256 mm
Matrix	256 x 256 x 192 (rotated!)
Resolution	1 mm isotropic
TR	2250 ms
TI	900 ms
TE	2.98 ms
Flip angle	9 deg
Parallel imaging	GRAPPA Acceleration factor PE: 2 Reference lines PE: 24

T2-weighted #

Turbo Spin Echo (TSE) #

Quick, high (in-plane) resolution, T₂-weighted, structural MRI (for incidental findings)

Parameter	Value
Acquisition time	1 min 38 s
Type	2D
Slices	29
Slice thickness	4 mm
Slice gap	30% (1.2 mm)
FOV	220 mm x 220 mm
Matrix	320 x 320
Resolution	0.7 mm x 0.7 mm
TR	5060 ms
TE	102 ms
Flip angle	140 deg
Parallel imaging	GRAPPA Acceleration factor PE: 2 Reference lines PE: 26

TSE FLAIR #

High (in-plane) resolution, T₂-weighted, ‘dark-fluid’, structural MRI (for incidental findings)

Parameter	Value
Acquisition time	4 min 32 s
Type	2D
Slices	25
Slice thickness	4 mm
Slice gap	30% (1.2 mm)
FOV	220 mm x 220 mm
Matrix	256 x 256
Resolution	0.9 mm x 0.9 mm
TR	9000 ms
TI	2500 ms
TE	100 ms
Flip angle	150 deg

Diffusion MRI #

High resolution, T₁-weighted, structural MRI

Parameter	Value
Acquisition time	8 min 52 s
Type	2D (Axial slices)
b-value	0, 1000
Number of directions	64 (256 possible with a larger TA)
FOV	192 mm x 192 mm
Matrix	96 x 96
Resolution	2 mm isotropic
TR	7800 ms
TE	90 ms
Flip angle
Parallel imaging	GRAPPA Acceleration factor PE: 2 Reference lines PE: 24

BOLD fMRI #

T_2*-weighted EPI sequences with BOLD contrast

Standard fMRI #

Functional MRI with 3 mm isotropic spatial resolution

EPI_Standard #

Standard fMRI, 2 s per volume

Parameter	Value
Acquisition time	2 s (per volume)
Type	2D
Slices	32
Slice thickness	3 mm
Slice gap	25% (0.75 mm)
Slice order	Descending (32 – 1)
FOV	192 mm x 192 mm
Matrix	64 x 64
Resolution	3 mm x 3 mm
TR	2000 ms
TE	30 ms
Flip angle	78 deg
Bandwidth	2112 Hz/Px
Echo spacing	0.54 ms

EPI_Standard_1s #

Standard fMRI, 1 s per volume with reduced brain coverage

Parameter	Value
Acquisition time	1 s (per volume)
Slices	16
Slice order	Descending (16 – 1)
TR	1000 ms
Bandwidth	2232 Hz/Px
Echo spacing	0.51 ms

Other parameters are those of EPI_Standard.

High Resolution fMRI #

Functional MRI with 2 mm isotropic or higher spatial resolution

EPI_HighRes_2iso #

fMRI with 2 mm isotropic spatial resolution, 2 s per volume. Keep in mind that the thinner slices leads to reduced brain coverage!

Parameter	Value
Acquisition time	2 s (per volume)
Type	2D
Slices	32
Slice thickness	2 mm
Slice gap	25% (0.5 mm)
Slice order	Descending (32 – 1)
FOV	192 mm x 192 mm
Matrix	96 x 96
Resolution	2 mm x 2 mm
TR	2000 ms
TE	30 ms
Flip angle	78 deg
Bandwidth	1628 Hz/Px
Echo spacing	0.7 ms
Parallel imaging	GRAPPA Acceleration factor PE: 2 Reference lines PE: 48

EPI_HighRes_2iso_WholeBrain #

fMRI with 2 mm isotropic spatial resolution, 40 slices for a whole brain coverage. Keep in mind that acquiring more slices leads to longer acquisition time!

Parameter	Value
Acquisition time	2.5 s (per volume)
Slices	40
TR	2500 ms

Other parameters are those of EPI_HighRes_2iso.

EPI_HighRes_2iso_LargerFOV #

fMRI with 2 mm isotropic spatial resolution, with a FOV of 205 mm for patricipants with larger head. Keep in mind that acquiring slices with larger FOV leads to slightly fewer slices thus slightly more reduced brain coverage!

Parameter	Value
Slices	30
FOV	205 mm x 205 mm
Matrix	102 x 102
Bandwidth	1400 Hz/Px
Echo spacing	0.8 ms

Other parameters are those of EPI_HighRes_2iso.

EPI_HighRes_1.5×1.5x2mm #

fMRI with 1.5 mm in-plane (highest achievable) spatial resolution, 2 s per volume. Keep in mind that acquiring slices with higher resolution leads to slightly fewer slices thus slightly more reduced brain coverage!

Parameter	Value
Acquisition time	2 s (per volume)
Slices	28
Matrix	128 x 128
Resolution	1.5 mm x 1.5 mm
Bandwidth	1502 Hz/Px
Echo spacing	0.75 ms

Other parameters are those of EPI_HighRes_2iso.

Fieldmap #

Magnetic field mapping sequences required to

• undistort EPI data (e.g. fMRI, DWI)
• measure functional sensitivity

 It has to be acquired with the same geometry (FOV, resolution, alignment, slice centre) as the EPI data! 

Standard Fieldmap #

Fieldmap with 3 mm isotropic spatial resolution. It matches with Standard fMRI sequences.

Fieldmapping #

Dual-echo fieldmap

Parameter	Value
Acquisition time	54 s
Type	2D
Slices	32
Slice thickness	3 mm
Slice gap	25% (0.75 mm)
FOV	192 mm x 192 mm
Matrix	64 x 64
Resolution	3 mm x 3 mm
TR	400 ms
TE	5.19 ms, 7.65 ms
Flip angle	60 deg

High Resolution Fieldmaps #

Fieldmaps 2 mm isotropic or higher spatial resolution. They match with High resolution fMRI sequences.

Fieldmapping_2iso #

High resolution dual-echo fieldmap

Parameter	Value
Acquisition time	1 m 19 s
Type	2D
Slices	32
Slice thickness	2 mm
Slice gap	25% (0.5 mm)
FOV	192 mm x 192 mm
Matrix	96 x 96
Resolution	2 mm x 2 mm
TR	400 ms
TE	5.19 ms, 7.65 ms
Flip angle	60 deg

Fieldmapping_2iso_WholeBrain #

High resolution dual-echo fieldmap with whole brain coverage

Parameter	Value
Acquisition time	1 m 26 s
Slices	40
TR	437 ms

Other parameters are those of Fieldmapping_2iso.

Fieldmapping_2iso_LargerFOV #

High resolution dual-echo fieldmap with larger FOV

Parameter	Value
Acquisition time	1 m 24 s
Slices	30
FOV	205 mm x 205 mm
Matrix	102 x 102

Other parameters are those of Fieldmapping_2iso.

Fieldmapping_1.5×1.5x2mm #

High resolution dual-echo fieldmap with our highest achievable in-plane resolution

Parameter	Value
Acquisition time	1 m 45 s
Slices	32
Matrix	128 x 128
Resolution	1.5 mm x 1.5 mm

Other parameters are those of Fieldmapping_2iso.